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SubjectsPharmacologyCNSAntipsychotics

Antipsychotics

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Antipsychotics (neuroleptics) are the cornerstone of treatment for schizophrenia, acute psychosis, mania, and several off-label uses. They are split into typical (first-generation, FGA) and atypical (second-generation, SGA) agents, and almost every exam-relevant fact flows from one core mechanism — dopamine D2 receptor blockade — and its consequences across the four dopaminergic pathways. Antipsychotics relieve th

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