AT

Chronic Lymphocytic Leukaemia (CLL) — Practice

Q1.Easy
A 65-year-old man with chronic lymphocytic leukaemia suddenly develops a rapidly enlarging lymph node, fever and weight loss. Biopsy now shows sheets of large transformed lymphoid cells replacing the previous small-cell infiltrate. This aggressive transformation is best termed:
ABlast crisis
BLeukaemoid reaction
CRichter transformation
DLeukoerythroblastic reaction