Colorectal Carcinoma & Polyps
HardHigh-yieldPathology · GIT & Liver
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Colorectal carcinoma (CRC) is the prototype of the adenoma–carcinoma sequence, where a benign neoplastic polyp accumulates stepwise genetic hits and turns malignant. This topic links surgical pathology, molecular genetics (APC, KRAS, p53, mismatch-repair genes) and staging — a perennial NEET PG favourite. Read it as one continuum: polyp → dysplasia → invasive carcinoma → metastasis. A polyp is any mass projecting …
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