AT

Cystic Renal Diseases — Topic Test

20 questions · exam mode (answers revealed at the end). 18 min suggested.

Q1.Hard#Clinical
A 50-year-old male presents with haematuria and a 4 cm renal mass on CT. Nephrectomy is performed. Gross examination shows a golden-yellow tumour confined to the kidney. Microscopically, the tumour cells have clear cytoplasm arranged in nests separated by a delicate vascular network. Loss of which gene is characteristically associated with this tumour?
AVHL (Von Hippel-Lindau) gene on chromosome 3p
BNF2 gene on chromosome 22q
CRB1 gene on chromosome 13q
DWT1 gene on chromosome 11p