Malignant Hyperthermia
HardHigh-yieldAnaesthesia · General Anaesthesia
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Malignant hyperthermia (MH) is a life-threatening, autosomal-dominant pharmacogenetic disorder of skeletal muscle in which exposure to volatile inhalational anaesthetics and/or the depolarising muscle relaxant succinylcholine triggers an uncontrolled rise in intracellular calcium, producing a fulminant hypermetabolic crisis. It is a high-yield, must-know anaesthesia emergency because recognition is clinical, the anti…
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