Mycobacterium leprae
ModerateMicrobiology · Bacteriology
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Mycobacterium leprae is an obligate intracellular acid-fast bacillus causing leprosy (Hansen's disease) — a chronic granulomatous disease primarily of the skin and peripheral nerves. It is unique among medical bacteria for being non-cultivable in vitro, having the longest generation time of any bacterium, and producing a disease whose entire clinical spectrum is decided by the host's cell-mediated immunity (CMI). …
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