One-Carbon Metabolism & Amino Acid Derivatives — Topic Test
20 questions · exam mode (answers revealed at the end). 18 min suggested.
A 52-year-old chronic alcoholic presents with macrocytic anaemia and hypersegmented neutrophils. His one-carbon metabolism is disturbed, and the trap of folate as 5-methyltetrahydrofolate cannot be released. Reactivation of this trapped folate pool depends on which vitamin-dependent enzyme?
ADihydrofolate reductase
BThymidylate synthase
CMethionine synthase
DSerine hydroxymethyltransferase