Opioid Analgesics in Anaesthesia
ModerateAnaesthesia · Pharmacology
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Opioids are the cornerstone of intra-operative analgesia and balanced anaesthesia, blunting the haemodynamic stress response to laryngoscopy and surgery. This note covers receptor pharmacology, the clinically vital concept of context-sensitive half-time, agent-by-agent comparison (morphine, fentanyl, remifentanil, tramadol), characteristic side-effects (rigidity, PONV, respiratory depression) and reversal with naloxo…
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