Prostaglandins, Leukotrienes & Eicosanoids
HardPharmacology · Autacoids
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Eicosanoids are 20-carbon oxygenated derivatives of arachidonic acid that act as locally-produced, short-lived autacoids ("local hormones") modulating inflammation, vascular tone, platelet function, gastric protection, uterine activity and bronchial calibre. This is a favourite NEET PG topic because the pathway logic directly explains the pharmacology of NSAIDs, montelukast, misoprostol and the classic aspirin-exacer…
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