Translation & Genetic Code — Topic Test
7 questions · exam mode (answers revealed at the end). 18 min suggested.
A 3-year-old child of consanguineous parents has coarse facies, corneal clouding, hepatosplenomegaly and high circulating lysosomal enzyme levels, yet fibroblast lysosomes are enzyme-deficient. The defect lies in the enzyme that tags lysosomal proteins. Which post-translational modification is impaired?
AMannose-6-phosphate addition
BN-linked core glycosylation
CTyrosine sulfation
DO-linked glycosylation